Área 7. Biotecnología. Aplicaciones Sanitarias de Biociencias
OBJETIVOS CIENTÍFICOS VINCULADOS AL PLAN ESTRATÉGICO
- Personal
- Publicaciones
- Listado Publicaciones
- Ayudas de Investigación
- Investigación Clínica
- Tesis Doctorales
11
Grupos de Investigación
- BIOLOGÍA DE LA REPRODUCCIÓN (CONSOLIDADO)
- BIOMEMBRANAS Y SEÑALIZACIÓN CELULAR (CONSOLIDADO)
- BIOQUIMICA Y BIOTECNOLOGIA ENZIMATICA (CONSOLIDADO)
- FISIOLOGÍA REPRODUCTIVA Y REPRODUCCIÓN ASISTIDA (CONSOLIDADO)
- BIOLOGÍA MOLECULAR DE SISTEMAS (CONSOLIDADO)
- INVESTIGACIÓN EN GINECOLOGÍA, REPRODUCCIÓN Y MEDICINA MATERNO-FETAL (CONSOLIDADO)
- TECNOLOGÍAS DE MODELADO, PROCESAMIENTO Y GESTIÓN DEL CONOCIMIENTO (CONSOLIDADO)
- GRUPO DE INVESTIGACIÓN EN RADIOLOGÍA (EMERGENTE)
- GRUPO DE RADIOFARMACIA (CLÍNICO ASOCIADO)
- GRUPO DE INVESTIGACIÓN EN FÍSICA MÉDICA (EMERGENTE)
- FARMACOCINETICA CLINICA Y FARMACOTERAPIA APLICADA (CLÍNICO ASOCIADO)
INDICADORES GENERALES
50
Nº Publicaciones
213.8
Impacto Total
4.28
Impacto Medio
| Tipo | Nº Pubs | FI total | FI Medio |
| Originales | 48 (96.0%) | 201.6 | 4.2 |
| Revisiones | 2 (4.0%) | 12.2 | 6.1 |
76.0
Q1%
20.0
D1%
0
FI >= 15
| Tipo | Nº Q1 | Nº D1 | Nº FI >= 15 |
| Originales | 36 | 9 | 0 |
| Revisiones | 2 | 1 | 0 |
INDICADORES DE LIDERAZGO
37
(74.0%)
Nº Publicaciones
165.7
Impacto Total
4.48
Impacto Medio
| Nº Pubs | FI total | FI Medio | |
| Mujer | 21 (56.76%) | 90.9 | 4.33 |
| Hombre | 16 (43.24%) | 74.8 | 4.68 |
78.38
Q1%
21.62
D1%
0
FI >= 15
| Nº Q1 | Nº D1 | Nº FI >= 15 | |
| Mujer | 16 | 4 | 0 |
| Hombre | 13 | 4 | 0 |
OTROS INDICADORES
14.15
HCP10% (2019-2023)
77.78
HCP10 Liderado% (2019-2023)
44.44
HCP10 Lid. Mujeres% (2019-2023)
1.13
Crown (2019-2023)
76.0
Open Access%
58.0
Col. International%
* Se muestran las 5 especies, los 10 genes y las 20 enfermedades más nombradas. Los valores están normalizados logarítmicamente en base al número de publicaciones.
INDICADORES EVOLUTIVOS
DESTACADAS
Cuenca-Guardiola J, de la Morena-Barrio B*, Garcia JL, ..., Fernandez-Breis JT*.
Improvement of large copy number variant detection by whole genome nanopore sequencing.
Journal of Advanced Research, 2023, 50, 145-158, PMID: 36323370, FI: 10.7
Navarro-Orcajada S, Conesa I, Vidal-Sanchez FJ, ..., Lopez-Nicolas JM*.
Stilbenes: Characterization, bioactivity, encapsulation and structural modifications. A review of their current limitations and promising approaches.
Critical Reviews in Food Science and Nutrition, 2023, 63, 7269-7287, PMID: 35234546, FI: 10.2
Guerrero-Rubio MA, Walker-Hale N, Guo R, ..., Gandia-Herrero F* et al.
Are seven amino acid substitutions sufficient to explain the evolution of high l-DOPA 4,5-dioxygenase activity leading to betalain pigmentation? Revisiting the gain-of-function mutants of Bean et al. (2018).
New Phytologist, 2023, 239, 2265-2276, PMID: 37243529, FI: 9.4
Martinez-Rodriguez P, Guerrero-Rubio MA, Hernandez-Garcia S, ..., Gandia-Herrero F*.
Characterization of betalain-loaded liposomes and its bioactive potential in vivo after ingestion.
Food Chemistry, 2023, 407, 135180, PMID: 36521390, FI: 8.8
Guerrero-Rubio MA, Hernandez-Garcia S, Garcia-Carmona F, Gandia-Herrero F*.
Consumption of commonly used artificial food dyes increases activity and oxidative stress in the animal model Caenorhabditis elegans.
Food Research International, 2023, 169, 112925, PMID: 37254351, FI: 8.1
LISTADO COMPLETO
Zapata-Perez R, Garcia-Saura AG, Scantlebery AML, ..., Sanchez-Ferrer A.
Biotechnological production of reduced and oxidized NAD(+) precursors.
Food Research International, 2023, 165, 112560, PMID: 36869544, FI: 8.1
Vinolas-Verges E, Ribas-Maynou J, Barranco I et al.
Chromatin condensation but not DNA integrity of pig sperm is greater in the sperm-rich fraction.
Journal of Animal Science and Biotechnology, 2023, 14, 139, PMID: 37926841, FI: 7.0
Barranco I, Sanchez-Lopez CM, Bucci D, ..., Roca J*.
The Proteome of Large or Small Extracellular Vesicles in Pig Seminal Plasma Differs, Defining Sources and Biological Functions.
Molecular & Cellular Proteomics, 2023, 22, 100514, PMID: 36796643, FI: 7.0
Gonzalez-Vidal A, Mercado-Saenz S, Burgos-Molina AM, ..., Alcaraz M* et al.
Molecular Mechanisms of Resistance to Ionizing Radiation in S. cerevisiae and Its Relationship with Aging, Oxidative Stress, and Antioxidant Activity.
Antioxidants, 2023, 12, PMID: 37759994, FI: 7.0
Gavira JA, Rico-Jimenez M, Ortega A et al.
Emergence of an Auxin Sensing Domain in Plant-Associated Bacteria.
Mbio, 2023, , e0336322, PMID: 36602305, FI: 6.4
Cuenca-Guardiola J, Morena-Barrio B, Navarro-Manzano E, ..., Corral J*, Fernandez-Breis JT*.
Detection and annotation of transposable element insertions and deletions on the human genome using nanopore sequencing.
Iscience, 2023, 26, 108214, PMID: 37953943, FI: 5.8
Belda-Perez R, Heras S, Cimini C, ..., Coy P*.
Advancing bovine in vitro fertilization through 3D printing: the effect of the 3D printed materials.
Frontiers in Bioengineering and Biotechnology, 2023, 11, 1260886, PMID: 37929185, FI: 5.7
Cerna-Vargas JP, Sanchez-Romera B, Matilla MA, Ortega A et al.
Sensing preferences for prokaryotic solute binding protein families.
Microbial Biotechnology, 2023, 16, 1823-1833, PMID: 37547952, FI: 5.7
Henarejos-Escudero P, Mendez-Garcia FF, Hernandez-Garcia S, ..., Gandia-Herrero F*.
Design, Synthesis and Gene Modulation Insights into Pigments Derived from Tryptophan-Betaxanthin, Which Act against Tumor Development in Caenorhabditis elegans.
International Journal of Molecular Sciences, 2023, 25, PMID: 38203234, FI: 5.6
Angulo J, Fernandez A, Sevilleja-Ortiz A, Sanchez-Ferrer A et al.
Upregulation of Orai Channels Contributes to Aging-Related Vascular Alterations in Rat Coronary Arteries.
International Journal of Molecular Sciences, 2023, 24, PMID: 37686206, FI: 5.6
Parra A, Padilla L, Lucas X, ..., Roca J*.
Seminal Extracellular Vesicles and Their Involvement in Male (In)Fertility: A Systematic Review.
International Journal of Molecular Sciences, 2023, 24, PMID: 36902244, FI: 5.6
Alcantud R, Weiss J, Terry MI, ..., Fernandez-Breis JT et al.
Flower transcriptional response to long term hot and cold environments in Antirrhinum majus.
Frontiers in Plant Science, 2023, 14, 1120183, PMID: 36778675, FI: 5.6
Navarro-Orcajada S, Vidal-Sanchez FJ, Conesa I, ..., Lopez-Nicolas JM*.
Improvement of the Physicochemical Limitations of Rhapontigenin, a Cytotoxic Analogue of Resveratrol against Colon Cancer.
Biomolecules, 2023, 13, PMID: 37627335, FI: 5.5
Toledo-Guardiola SM, Luongo C, Abril-Parreno L, ..., Matas C*.
Different seminal ejaculated fractions in artificial insemination condition the protein cargo of oviductal and uterine extracellular vesicles in pig.
Frontiers in Cell and Developmental Biology, 2023, 11, 1231755, PMID: 37868907, FI: 5.5
Lozano-Terol G, Gallego-Jara J, Sola-Martinez RA, ..., de Diego Puente T.
Regulation of the pyrimidine biosynthetic pathway by lysine acetylation of E. coli OPRTase.
Febs Journal, 2023, 290, 442-464, PMID: 35989594, FI: 5.4
Asensio Ruiz MA, Alonso Garcia A, Bravo-Ferrer Moreno ML, ..., Martinez Martinez T.
In Vitro Hemocompatibility and Genotoxicity Evaluation of Dual-Labeled [(99m)Tc]Tc-FITC-Silk Fibroin Nanoparticles for Biomedical Applications.
, 2023, 16, PMID: 37259395, FI: 5.215
Canha-Gouveia A, Perez-Prieto I, Rodriguez CM et al.
The female upper reproductive tract harbors endogenous microbial profiles.
Frontiers in Endocrinology, 2023, 14, 1096050, PMID: 37415669, FI: 5.2
Alvarez-Rodriguez M, Roca J, Martinez EA et al.
Mating modifies the expression of crucial oxidative-reductive transcripts in the pig oviductal sperm reservoir: is the female ensuring sperm survival?
Frontiers in Endocrinology, 2023, 14, 1042176, PMID: 37351104, FI: 5.2
Minig L, Gracia Segovia M, Arencibia O et al.
Oncological outcomes among young women with non-epithelial ovarian cancer: the YOC-Care study (Young Ovarian Cancer - Care).
International Journal of Gynecological Cancer, 2023, ijgc-2022-004162 [pii], PMID: 36796862, FI: 4.8
Navarro-Orcajada S, Vidal-Sanchez FJ, Conesa I, ..., Lopez-Nicolas JM*.
Antiproliferative Effects in Colorectal Cancer and Stabilisation in Cyclodextrins of the Phytoalexin Isorhapontigenin.
Biomedicines, 2023, 11, PMID: 38002023, FI: 4.7
Luongo C, Llamas-Lopez PJ, Garrappa G, ..., Garcia-Vazquez FA*.
Impact of inclusion of post-spermatic ejaculate fraction in boar seminal doses on sperm metabolism, quality, and interaction with uterine fluid.
Scientific Reports, 2023, 13, 15258, PMID: 37709904, FI: 4.6
Castell-Diaz J*, Minarro-Gimenez JA, Martinez-Costa C*.
Supporting SNOMED CT postcoordination with knowledge graph embeddings.
Journal of Biomedical Informatics, 2023, 139, 104297, PMID: 36736448, FI: 4.5
Parrilla I, Cambra JM, Cuello C, ..., Gil MA*, Martinez EA.
Cryopreservation of highly extended pig spermatozoa remodels its proteome and counteracts polyspermic fertilization in vitro.
Andrology, 2023, 10.1111/andr.13575 [doi], PMID: 38131448, FI: 4.5
Garcia-Diaz JA, Garcia-Sanchez F, Valencia-Garcia R*.
Smart Analysis of Economics Sentiment in Spanish Based on Linguistic Features and Transformers
Ieee Access, 2023, 11, PMID: null, FI: 3.9
Abad-Navarro F, Martinez-Costa C, Fernandez-Breis JT*.
HURON: A Quantitative Framework for Assessing Human Readability in Ontologies
Ieee Access, 2023, 11, PMID: null, FI: 3.9
Gonzalez-Lopez A*.
Technical note: Characteristics of the energy spread kernels of scattered radiation in an x-ray room.
Medical Physics, 2023, 50, 643-650, PMID: 35908179, FI: 3.8
Pan R, Garcia-Diaz JA, Garcia-Sanchez F, Valencia-Garcia R*.
Evaluation of transformer models for financial targeted sentiment analysis in Spanish.
Peerj Computer Science, 2023, 9, e1377, PMID: 37346571, FI: 3.8
Sola-Martinez RA, Zeng J, Awchi M et al.
Preservation of exhaled breath samples for analysis by off-line SESI-HRMS: proof-of-concept study.
Journal of Breath Research, 2023, 18, PMID: 38029449, FI: 3.8
Illueca Fernandez E, Fernandez Llatas C, Jara Valera AJ, Fernandez Breis JT et al.
Sequence-oriented sensitive analysis for PM2.5 exposure and risk assessment using interactive process mining.
Plos one, 2023, 18, e0290372, PMID: 37616197, FI: 3.7
Monteagudo-Cascales E, Ortega A, Velando F et al.
Study of NIT domain-containing chemoreceptors from two global phytopathogens and identification of NIT domains in eukaryotes.
Molecular Microbiology, 2023, 119, 739-751, PMID: 37186477, FI: 3.6
Abril-Parreno L, Carthy TR, Keogh K et al.
Genome-wide association study reveals candidate markers related to field fertility and semen quality traits in Holstein-Friesian bulls.
Animal, 2023, 17, 100841, PMID: 37224615, FI: 3.6
Abril-Parreno L, Druart X, Fair S et al.
Metabolic signature of cervical mucus in ewe breeds with divergent cervical sperm transport: a focus on metabolites involved in amino acid metabolism.
Metabolomics, 2023, 19, 59, PMID: 37338596, FI: 3.6
Gonzalez-Lopez A*.
Improving input contrast estimation to an x-ray imaging system.
Physics in Medicine and Biology, 2023, 10.1088/1361-6560/ad0534 [doi], PMID: 37857333, FI: 3.5
Padilla L, Barranco I, Martinez-Hernandez J, ..., Pastor LM et al.
Extracellular vesicles would be involved in the release and delivery of seminal TGF-beta isoforms in pigs.
, 2023, 10, 1102049, PMID: 36846267, FI: 3.471
Pineiro-Silva C, Navarro-Serna S, Belda-Perez R, Gadea J*.
Production of Genetically Modified Porcine Embryos via Lipofection of Zona-Pellucida-Intact Oocytes Using the CRISPR/Cas9 System.
Animals, 2023, 13, PMID: 36766231, FI: 3.0
Ramirez-Gonzalez D, Poto A, Peinado B, ..., Ruiz S*.
Ultrasonography of Pregnancy in Murciano-Granadina Goat Breed: Fetal Growth Indices and Umbilical Artery Doppler Parameters.
Animals, 2023, 13, PMID: 36830405, FI: 3.0
Gonzalez-Ramiro H, Gil MA, Cuello C, ..., Parrilla I*, ..., Martinez EA.
The Use of a Brief Synchronization Treatment after Weaning, Combined with Superovulation, Has Moderate Effects on the Gene Expression of Surviving Pig Blastocysts.
Animals, 2023, 13, PMID: 37174605, FI: 3.0
Parraga-Ros E, Alvarez-Martin U, Seva J, ..., Romar R*.
The impact of in vitro embryo production on placental and umbilical cord vascularization is minimized by the addition of reproductive fluids.
Theriogenology, 2023, 208, 149-157, PMID: 37329589, FI: 2.8
Stiavnicka M, Hosek P, Abril-Parreno L et al.
Membrane remodulation and hyperactivation are impaired in frozen-thawed sperm of low-fertility bulls.
Theriogenology, 2023, 195, 115-121, PMID: 36332370, FI: 2.8
Gonzalez-Plaza A, Cambra JM, Garcia-Canovas M, ..., Martinez CA*, Cuello C.
Cryotop vitrification of large batches of pig embryos simultaneously provides excellent postwarming survival rates and minimal interference with gene expression.
Theriogenology, 2023, 206, 1-10, PMID: 37148716, FI: 2.8
Canha-Gouveia A, Di Nisio V, Salumets A et al.
The Upper Reproductive System Microbiome: Evidence beyond the Uterus.
Seminars in Reproductive Medicine, 2023, 41, 190-199, PMID: 38320577, FI: 2.7
Garcia C, Prieto MT, Escudero F, ..., De Paco Matallana C.
The impact of early versus delayed cord clamping on hematological and cardiovascular changes in preterm newborns between 24 and 34 weeks' gestation: a randomized clinical trial.
Archives of Gynecology and Obstetrics, 2023, 10.1007/s00404-023-07119-0 [doi], PMID: 37436461, FI: 2.6
Cortes-Sandoval S, Seco-Rovira V*, Beltran-Frutos E, ..., Pastor LM*.
Heterogeneity of mesenchymal cells in human amniotic membrane at term.
Histology and Histopathology, 2023, , 18660, PMID: 37721417, FI: 2.0
Diaz LS, Navalon CI, Espin RG et al.
Impact of proactive of infliximab monitoring using the Bayesian approach in the maintenance phase in patients with inflammatory bowel disease.
Gastroenterologia y Hepatologia, 2023, 46, 504-511, PMID: 36400260, FI: 1.9
Serrano Diaz L, Iniesta Navalon C, Gomez Espin R, ..., Bernal Morell E et al.
Comparative effectiveness and drug survival of biosimilar infliximab CPT-13 vs. reference infliximab in inflammatory bowel disease: A retrospective cohort study.
Gastroenterologia y Hepatologia, 2023, S0210-5705(23)00392-8 [pii], PMID: 37597745, FI: 1.9
AYUDAS CONCEDIDAS EN 2023
TOTAL DE AYUDAS CONCEDIDAS
8
Nº Ayudas
0.85M €
Financiación
TOTAL DE AYUDAS RECURSOS HUMANOS CONCEDIDAS
2
Nº Ayudas
0.11M €
Financiación
TOTAL DE AYUDAS PROYECTOS I+D+i CONCEDIDAS
0
Nº Ayudas Europeas
0.0M €
Financiación Europea
4
Nº Ayudas Nacionales
0.49M €
Financiación Nacional
2
Nº Ayudas Regionales
0.25M €
Financiación Regional
TOTAL DE REDES CONCEDIDAS
0
Nº Ayudas
0.0M €
Financiación
OTRAS AYUDAS COMPETITIVAS CONCEDIDAS (MOVILIDAD, ORGANIZACIÓN DE EVENTOS CIENTÍFICOS, ...)
0
Nº Ayudas
0.0K €
Financiación
PROYECTOS DE I+D+i Y AYUDAS DE RRHH ACTIVAS EN 2023
23
TOTAL AYUDAS
1
RECURSOS HUMANOS
0
REDES
0
PROYECTOS INTERNACIONALES
14
PROYECTOS NACIONALES
8
PROYECTOS REGIONALES
INICIADA EN 2023
1
Nº Estudios
1
Nº Ensayos Clínicos
0
Nº Producto Sanitario
0
Nº Estudios Post-Autorización
0
Nº Otros Estudios
ACTIVOS EN 2023
9
Nº Estudios
4
Nº Ensayos Clínicos
1
Nº Producto Sanitario
0
Nº Estudios Post-Autorización
4
Nº Otros Estudios
FACTURACIÓN EN 2023
0.26M €
Facturado
8
Nº Tesis (0 con mención internacional)
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