MEMORIA 2023 - Área 6. Inmunología, Microbiología y Enfermedades Infecciosas

Área 6. Inmunología, Microbiología y Enfermedades Infecciosas

OBJETIVOS CIENTÍFICOS VINCULADOS AL PLAN ESTRATÉGICO

9 Grupos de Investigación

INMUNOLOGÍA E INMUNOTOLERANCIA EN TRASPLANTES Y ENFERMEDADES DE BASE INMUNOLÓGICA (CONSOLIDADO)
INMUNIDAD, INFLAMACIÓN Y CÁNCER (CONSOLIDADO)
TRASPLANTE HEMATOPOYÉTICO / TERAPIA CELULAR (CONSOLIDADO)
INMUNIDAD INNATA EN LA SALUD Y LA ENFERMEDAD (EMERGENTE)
PATOLOGÍA INFECCIOSA, MICROBIOLOGÍA CLÍNICA Y MEDICINA TROPICAL (EMERGENTE)
ONCOLOGÍA CLÍNICA Y TRASLACIONAL (CLÍNICO ASOCIADO)
AUTOFAGIA, RESPUESTA INMUNE Y TOLERANCIA EN PROCESOS PATOLÓGICOS (EMERGENTE)
BIOINGENIERÍA TISULAR Y MEDICINA REGENERATIVA (EMERGENTE)
FARMACIA CLÍNICA Y TERAPÉUTICA (CLÍNICO ASOCIADO)

INDICADORES GENERALES

Nº Publicaciones

668.7

Impacto Total

6.75

Impacto Medio

Tipo	Nº Pubs	FI total	FI Medio
Originales	90 (90.91%)	610.3	6.78
Revisiones	9 (9.09%)	58.4	6.49

71.72

Q1%

38.38

D1%

FI >= 15

Tipo	Nº Q1	Nº D1	Nº FI >= 15
Originales	62	35	6
Revisiones	9	3	0

INDICADORES DE LIDERAZGO

57 (58.0%)

Nº Publicaciones

232.7

Impacto Total

4.08

Impacto Medio

	Nº Pubs	FI total	FI Medio
Mujer	25 (43.86%)	110.5	4.42
Hombre	32 (56.14%)	122.2	3.82

68.42

Q1%

29.82

D1%

FI >= 15

	Nº Q1	Nº D1	Nº FI >= 15
Mujer	19	10	0
Hombre	20	7	0

OTROS INDICADORES

22.27

HCP10% (2019-2023)

34.38

HCP10 Liderado% (2019-2023)

17.71

HCP10 Lid. Mujeres% (2019-2023)

2.21

Crown (2019-2023)

85.86

Open Access%

33.33

Col. International%

* Se muestran las 5 especies, los 10 genes y las 20 enfermedades más nombradas. Los valores están normalizados logarítmicamente en base al número de publicaciones.

INDICADORES EVOLUTIVOS

DESTACADAS

Candel S*, Tyrkalska SD, Alvarez-Santacruz C, Mulero V*. The nasopharyngeal microbiome in COVID-19. Emerging Microbes & Infections, 2023, , 2165970, PMID: 36606725, FI: 13.2

Tyrkalska SD, Candel S*, Pedoto A, ..., Cayuela ML*, Mulero V*. Zebrafish models of COVID-19. Fems Microbiology Reviews, 2023, 47, PMID: 36323404, FI: 11.3

Rodriguez-Ruiz L*, Lozano-Gil JM*, Naranjo-Sanchez E, ..., Mulero V. ZAKalpha/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome. Embo Molecular Medicine, 2023, 15, e18142, PMID: 37675820, FI: 11.1

Fan J, Hale VL, Lelieveld LT, ..., Roca FJ et al. Gaucher disease protects against tuberculosis. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120, e2217673120, PMID: 36745788, FI: 11.1

Martinez-Lopez A*, Candel S*, Tyrkalska SD. Animal models of silicosis: fishing for new therapeutic targets and treatments. European Respiratory Review, 2023, 32, PMID: 37558264, FI: 7.5

LISTADO COMPLETO

Pairo-Castineira E, Rawlik K, Bretherick AD et al. COLABORADORES: Clohisey S, Millar J, Shankar-Hari M, ..., Bernal E et al. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature, 2023, 10.1038/s41586-023-06034-3 [doi], PMID: 37198478, FI: 64.8

Hurvitz SA, Bardia A, Quiroga V, ..., Alonso-Romero JL et al. Neoadjuvant palbociclib plus either giredestrant or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase 2 study. Lancet Oncology, 2023, 24, 1029-1041, PMID: 37657462, FI: 51.1

Oliver-Caldes A, Gonzalez-Calle V, Cabanas V et al. Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study. Lancet Oncology, 2023, 24, 913-924, PMID: 37414060, FI: 51.1

Vergote I, Perez-Fidalgo JA, Hamilton EP, ..., Martinez-Garcia J et al. Oral Selinexor as Maintenance Therapy After First-Line Chemotherapy for Advanced or Recurrent Endometrial Cancer. Journal of Clinical Oncology, 2023, 41, 5400-5410, PMID: 37669480, FI: 45.3

Kurtz JE, Pujade-Lauraine E, Oaknin A, ..., Martinez Garcia J et al. Atezolizumab Combined With Bevacizumab and Platinum-Based Therapy for Platinum-Sensitive Ovarian Cancer: Placebo-Controlled Randomized Phase III ATALANTE/ENGOT-ov29 Trial. Journal of Clinical Oncology, 2023, 41, 4768-4778, PMID: 37643382, FI: 45.3

Martin-Broto J, Martinez-Garcia J, Moura DS et al. Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/ CDKN2A. Signal Transduction and Targeted Therapy, 2023, 8, 405, PMID: 37875500, FI: 39.3

Schlotawa L, Lopez A, Sanchez-Elexpuru G et al. An inducible expression system for the manipulation of autophagic flux in vivo. Autophagy, 2023, 19, 1582-1595, PMID: 36310368, FI: 13.3

Pinana JL, Vazquez L, Calabuig M, ..., Sanchez-Salinas A et al. One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients. Blood Cancer Journal, 2023, 13, 8, PMID: 36599843, FI: 12.8

Escrihuela-Vidal F, Berbel D, Fernandez-Hidalgo N et al. COLABORADORES: Sanchez FF, de Lomas JMG, Rosas G, ..., Vazquez EG et al. Impact of Intermediate Susceptibility to Penicillin on Antimicrobial Treatment and Outcomes of Endocarditis Caused by Viridans and Gallolyticus Group Streptococci. Clinical Infectious Diseases, 2023, 77, 1273-1281, PMID: 37345869, FI: 11.8

Fernandez-Miranda I, Pedrosa L, Llanos M, ..., Marin M et al. Monitoring of Circulating Tumor DNA Predicts Response to Treatment and Early Progression in Follicular Lymphoma: Results of a Prospective Pilot Study. Clinical Cancer Research, 2023, 29, 209-220, PMID: 36269794, FI: 11.5

Luciano AM, Di Martile M, Perez-Oliva AB et al. Exploring association of melanoma-specific Bcl-xL with tumor immune microenvironment. Journal of Experimental & Clinical Cancer Research, 2023, 42, 178, PMID: 37488586, FI: 11.3

Hidalgo-Tenorio C, Sadyrbaeva-Dolgova S, Enriquez-Gomez A, ..., Vazquez EG et al. EN-DALBACEN 2.0 Cohort: real-life study of dalbavancin as sequential/consolidation therapy in patients with infective endocarditis due to Gram-positive cocci. International Journal of Antimicrobial Agents, 2023, 62, 106918, PMID: 37442488, FI: 10.8

Lakhwani S, Rosinol L, Puig N, ..., De Arriba F et al. Recovery of uninvolved heavy/light chain pair immunoparesis in newly diagnosed transplant-eligible myeloma patients complements the prognostic value of minimal residual disease detection. Haematologica, 2023, 10.3324/haematol.2023.284154 [doi], PMID: 38031761, FI: 10.1

Mandaglio-Collados D, Lopez-Galvez R, Ruiz-Alcaraz AJ, ..., Rivera-Caravaca JM. Impact of particulate matter on the incidence of atrial fibrillation and the risk of adverse clinical outcomes: A review. Science of the Total Environment, 2023, 880, 163352, PMID: 37023806, FI: 9.8

Royo-Villanova M, Minambres E, Sanchez JM, ..., de Paco Tudela G et al. Maintaining the permanence principle of death during normothermic regional perfusion in controlled donation after the circulatory determination of death: Results of a prospective clinical study. American Journal of Transplantation, 2023, S1600-6135(23)00696-2 [pii], PMID: 37739346, FI: 8.8

Herrera-Hidalgo L, Munoz P, Alvarez-Uria A et al. COLABORADORES: Sanchez FF, de Lomas JMG, Rosas G, ..., Vazquez EG et al. Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort. International Journal of Infectious Diseases, 2023, 137, 134-143, PMID: 37926195, FI: 8.4

Moya-Quiles MR*, Muro M*. Characterization of two new HLA class I alleles: HLA-B*35:572 and HLA-C*04:491. Hla, 2023, 10.1111/tan.14966 [doi], PMID: 36607232, FI: 8.0

Castro-Santos P, Rojas-Martinez A, Riancho JA et al. COLABORADORES: Abellan J, Acosta-Isaac R, Aguado JM, ..., Garcia-Vazquez E et al. HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19. Hla, 2023, 102, 731-739, PMID: 37528566, FI: 8.0

Velez-Pinto JF, Garcia-Arranz M, Garcia-Bernal D et al. Therapeutic effect of adipose-derived mesenchymal stem cells in a porcine model of abdominal sepsis. Stem Cell Research & Therapy, 2023, 14, 365, PMID: 38087374, FI: 7.5

Villalba-Lopez F, Garcia-Bernal D*, Mateo SV, ..., Baroja-Mazo A*. Endothelial cell activation mediated by cold ischemia-released mitochondria is partially inhibited by defibrotide and impacts on early allograft function following liver transplantation. Biomedicine & Pharmacotherapy, 2023, 167, 115529, PMID: 37729732, FI: 7.5

Bernal-Bermudez B, Martinez-Lopez A*, Martinez-Morcillo FJ, ..., Garcia-Moreno D. A zebrafish model of Ifih1-driven Aicardi-Goutieres syndrome reproduces the interferon signature and the exacerbated inflammation of patients. Frontiers in Immunology, 2023, 14, 1294766, PMID: 38077314, FI: 7.3

Lopez Soto A, Velasco Martinez M, Ferrandez Martinez M, ..., Marin Sanchez P*. Prenatal ambiguous/atypical genitalia: why are we still missing it and how can we improve diagnosis? Ultrasound in Obstetrics & Gynecology, 2023, 10.1002/uog.27507 [doi], PMID: 37773980, FI: 7.1

Valentin MO, Crespo M, Fernandez C, Muro M et al. Improving the Access of Highly Sensitized Patients to Kidney Transplantation From Deceased Donors: The Spanish PATHI Program With Allocation Based on the Virtual Crossmatch. Transplantation, 2023, 10.1097/TP.0000000000004824 [doi], PMID: 37867239, FI: 6.2

Hofmann N, Lafarge X, Antica M, ..., Nicolas FJ* et al. Expert Consideration on Regulatory Aspects for Perinatal Derivatives in Clinical Settings. Stem Cells Translational Medicine, 2023, 12, 258-265, PMID: 37027834, FI: 6.0

Gramignoli R, Hofmann N, Agudo-Barriuso M, ..., Nicolas FJ* et al. Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives. Stem Cells Translational Medicine, 2023, szad068 [pii], PMID: 38071447, FI: 6.0

Stelling-Ferez J, Lopez-Miranda S, Gabaldon JA, Nicolas FJ*. Oleanolic Acid Complexation with Cyclodextrins Improves Its Cell Bio-Availability and Biological Activities for Cell Migration. International Journal of Molecular Sciences, 2023, 24, PMID: 37834307, FI: 5.6

Akbari Aghdam M, Romecin P, Garcia-Estan J, Atucha NM*. Role of Nitric Oxide in the Altered Calcium Homeostasis of Platelets from Rats with Biliary Cirrhosis. International Journal of Molecular Sciences, 2023, 24, PMID: 37446122, FI: 5.6

Del Pozo-Valero M, Corton M, Lopez-Rodriguez R, ..., Perez-Tomas ME et al. Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years. Geroscience, 2023, 45, 543-553, PMID: 36184726, FI: 5.6

Jimenez-Coll V, Llorente S, Boix F, ..., Muro M*. Monitoring of Serological, Cellular and Genomic Biomarkers in Transplantation, Computational Prediction Models and Role of Cell-Free DNA in Transplant Outcome. International Journal of Molecular Sciences, 2023, 24, PMID: 36835314, FI: 5.6

Candel S*, Tyrkalska SD, Perez-Sanz F, ..., Mulero V*. Analysis of 16S rRNA Gene Sequence of Nasopharyngeal Exudate Reveals Changes in Key Microbial Communities Associated with Aging. International Journal of Molecular Sciences, 2023, 24, PMID: 36835535, FI: 5.6

Alfaro R, Rodriguez-Aguilar L, Llorente S, ..., Muro M. Early Cytomegalovirus Reactivation in Renal Recipients Is Associated with High Levels of B Cell Maturation Antigen Transcript Expression Prior to Transplantation. International Journal of Molecular Sciences, 2023, 24, PMID: 37445668, FI: 5.6

Liarte S, Bernabe-Garcia A, Rodriguez-Valiente M, ..., Nicolas FJ. Amniotic Membrane Restores Chronic Wound Features to Normal in a Keratinocyte TGF-beta-Chronified Cell Model. International Journal of Molecular Sciences, 2023, 24, PMID: 37047181, FI: 5.6

Stelling-Ferez J, Cappellacci I, Pandolfi A, ..., Nicolas FJ*. Oleanolic acid rescues critical features of umbilical vein endothelial cells permanently affected by hyperglycemia. Frontiers in Endocrinology, 2023, 14, 1308606, PMID: 38192424, FI: 5.2

Sojo-Dorado J, Lopez-Hernandez I, Hernandez-Torres A et al. Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial. Journal of Antimicrobial Chemotherapy, 2023, 78, 1658-1666, PMID: 37260299, FI: 5.2

Suarez-Garcia I, Alejos B, Hernando V et al. COLABORADORES: Moreno S, Jarrin I, Dalmau D, ..., Bernal E et al. Effectiveness and tolerability of dolutegravir/lamivudine for the treatment of HIV-1 infection in clinical practice. Journal of Antimicrobial Chemotherapy, 2023, dkad102 [pii], PMID: 37099559, FI: 5.2

Suarez-Martinez C*, Santaella-Pascual M, Yague-Guirao G, Martinez-Gracia C. Infant gut microbiota colonization: influence of prenatal and postnatal factors, focusing on diet. Frontiers in Microbiology, 2023, 14, 1236254, PMID: 37675422, FI: 5.2

Gracia-Ahufinger I, Lopez-Gonzalez L, Vasallo FJ, ..., Yague-Guirao G* et al. The CARBA-MAP study: national mapping of carbapenemases in Spain (2014-2018). Frontiers in Microbiology, 2023, 14, 1247804, PMID: 37744921, FI: 5.2

Lopez-Garcia S, Aznar-Cervantes SD, Pagan A, ..., Rodriguez-Lozano FJ* et al. 3D Graphene/silk fibroin scaffolds enhance dental pulp stem cell osteo/odontogenic differentiation. Dental Materials, 2023, S0109-5641(23)00492-X [pii], PMID: 38114344, FI: 5.0

Pinana JL, Martino R, Vazquez L, ..., Sanchez-Salinas A et al. SARS-CoV-2-reactive antibody waning, booster effect and breakthrough SARS-CoV-2 infection in hematopoietic stem cell transplant and cell therapy recipients at one year after vaccination. Bone Marrow Transplantation, 2023, , 1-14, PMID: 36854892, FI: 4.8

Tilmont R, Yakoub-Agha I, Eikema DJ, ..., Moraleda JM et al. Carfilzomib, lenalidomide and dexamethasone followed by a second ASCT is an effective strategy in first relapse multiple myeloma: a study on behalf of the Chronic malignancies working party of the EBMT. Bone Marrow Transplantation, 2023, 58, 1182-1188, PMID: 37543712, FI: 4.8

Espinosa-Ruiz C, Esteban MA et al. Modulation of cell migration and cell tracking of the gilthead seabream (Sparus aurata) SAF-1 cells by probiotics. Fish & Shellfish Immunology, 2023, 142, 109149, PMID: 37858786, FI: 4.7

Serna-Duque JA, Espinosa-Ruiz C, Esteban MA et al. Hepcidin and piscidin modulation and antibacterial response in gilthead seabream (Sparus aurata) infected with Vibrio harveyi. Fish & Shellfish Immunology, 2023, 139, 108899, PMID: 37353061, FI: 4.7

Guebebia S, Espinosa-Ruiz C, Zourgui L et al. Effects of okra (Abelmoschus esculentus L.) leaves, fruits and seeds extracts on European sea bass (Dicentrarchus labrax) leukocytes, and their cytotoxic, bactericidal and antioxidant properties. Fish & Shellfish Immunology, 2023, 138, 108799, PMID: 37187214, FI: 4.7

Espinosa-Ruiz C, Gonzalez-Fernandez C, Cormier B et al. Immunotoxicological effects of perfluorooctanesulfonic acid on European seabass are reduced by polyethylene microplastics. Fish & Shellfish Immunology, 2023, 137, 108793, PMID: 37146847, FI: 4.7

Albaladejo-Riad N, Espinosa-Ruiz C, Esteban MA et al. Skin mucus metabolomics provides insights into the interplay between diet and wound in gilthead seabream (Sparus aurata). Fish & Shellfish Immunology, 2023, 134, 108590, PMID: 36746227, FI: 4.7

Garcia-Alvarez MA, Gonzalez-Fernandez C, Esteban MA et al. Molecular characterization of the cytotoxic and regulatory T cell coreceptor (CRTAM), and its ligand CADM1, in the European seabass and gilthead seabream. Fish & Shellfish Immunology, 2023, 134, 108569, PMID: 36720375, FI: 4.7

Cervera L, Gonzalez-Fernandez C, Cano D et al. Immunity elicited by AMP-encoding plasmids fails to increase the protection of European sea bass against nodavirus. Fish & Shellfish Immunology, 2023, 132, 108507, PMID: 36581252, FI: 4.7

Legaz I*, Morales R, Bolarin JM, ..., Muro M*. Is the Development of Ascites in Alcoholic Liver Patients Influenced by Specific KIR/HLA Gene Profiles? Biomedicines, 2023, 11, PMID: 37760846, FI: 4.7

Arguelles A, Sanchez-Fresneda R, Guirao-Abad JP, ..., Arguelles JC*. Insight into the Antifungal Effects of Propolis and Carnosic Acid-Extension to the Pathogenic Yeast Candida glabrata: New Propolis Fractionation and Potential Synergistic Applications. Journal of Fungi, 2023, 9, PMID: 37108897, FI: 4.7

Rodriguez-Lozano FJ*, Lopez-Garcia S, Sanchez-Bautista S et al. Effect of milled and lithography-based additively manufactured zirconia (3Y-TZP) on the biological properties of human osteoblasts. Journal of Prosthetic Dentistry, 2023, 130, 889-896, PMID: 35264309, FI: 4.6

Lopez-Lopez D, Roldan G, Fernandez-Rueda JL et al. COLABORADORES: Alonso A, Salgado-Garrido J, Pasalodos-Sanchez S, ..., Guillen E et al. A crowdsourcing database for the copy-number variation of the Spanish population. Human Genomics, 2023, 17, 20, PMID: 36894999, FI: 4.5

Cuesta A, Espinosa C, Esteban MA et al. Application of transcriptomic profiling to investigate the toxicity mechanisms caused by dietary exposure of nanoplastics in fish. Aquatic Toxicology, 2023, 264, 106712, PMID: 37813046, FI: 4.5

Sanchez Martinez DA*, Carrasco Picazo JP, Estrella Porter PD et al. Resident physician duty hours, resting times and European Working Time Directive compliance in Spain: a cross-sectional study. Human Resources for Health, 2023, 21, 70, PMID: 37620869, FI: 4.5

Garcia-Fernandez JJ, Sanchez-Nicolas JA, Galicia-Puyol S, ..., Bernal-Morell E et al. Failure of Non-Invasive Respiratory Support in Patients with SARS-CoV-2. Journal of Clinical Medicine, 2023, 12, PMID: 37892675, FI: 3.9

Bernal E, Garcia-Villalba E, Pons E, ..., Minguela A. Role of vaccination and anti-SARS-CoV-2 antibodies in the clinical outcome of hospitalized COVID-19 patients. Medicina Clinica, 2023, S0025-7753(23)00018-0 [pii], PMID: 36813683, FI: 3.9

Bernal E*, Garcia-Villalba E, Pons E, ..., Minguela A*. Remdesivir plus dexamethasone is associated to improve the clinical outcome of COVID-19 hospitalized patients regardless of their vaccination status. Medicina Clinica, 2023, S0025-7753(23)00173-2 [pii], PMID: 37100681, FI: 3.9

Gomez I, Lopez MC, Egui A, ..., Carrilero B et al. Differential expression profile of genes involved in the immune response associated to progression of chronic Chagas disease. Plos Neglected Tropical Diseases, 2023, 17, e0011474, PMID: 37440604, FI: 3.8

Alarcon-Linares ME, Moreno-Docon A*, Perez-Serna L et al. Rare Recombinant GI.5[P4] Norovirus That Caused a Large Foodborne Outbreak of Gastroenteritis in a Hotel in Spain in 2021. Microbiology Spectrum, 2023, 11, e0485722, PMID: 36809021, FI: 3.7

Alonso-Navarro R, Ramirez M, Masia M, ..., Bernal E et al. Time from symptoms onset to remdesivir is associated with the risk of ICU admission: a multicentric analyses. , 2023, 23, 286, PMID: 37142994, FI: 3.667

Esquerda M, Garcia-Estan J, Ruiz-Rosales A, ..., Millan J*. Academic climate and psychopathological symptomatology in Spanish medical students. Bmc Medical Education, 2023, 23, 843, PMID: 37936105, FI: 3.6

Morales R, Bolarin JM, Muro M, Legaz I. Presence of KIR2DL2/S2, KIR2DL5, and KIR3DL1 Molecules in Liver Transplant Recipients with Alcoholic Cirrhosis Could Be Implicated in Death by Graft Failure. Diagnostics, 2023, 13, PMID: 37046435, FI: 3.6

Jimenez-Coll V, El Kaaoui El Band J, Llorente S, ..., Muro M. All That Glitters in cfDNA Analysis Is Not Gold or Its Utility Is Completely Established Due to Graft Damage: A Critical Review in the Field of Transplantation. Diagnostics, 2023, 13, PMID: 37370877, FI: 3.6

Cuenca I, Botella C, Moya-Quiles MR, ..., Muro M. Genotypic Frequencies of Mutations Associated with Alpha-1 Antitrypsin Deficiency in Unrelated Bone Marrow Donors from the Murcia Region Donor Registry in the Southeast of Spain. Diagnostics, 2023, 13, PMID: 37685383, FI: 3.6

Espanol I, Leal JD, Blanquer M, ..., Moraleda JM. N-Acetylcistein for thrombotic thrombocytopenic purpura: an observational case series study. Annals of Hematology, 2023, 102, 2069-2075, PMID: 37171598, FI: 3.5

Sanchez-Villalobos M, Campos Banos E, Juan Fita MJ, ..., Salido Fierrez E*, Perez-Oliva AB*. A Newborn Screening Program for Sickle Cell Disease in Murcia (Spain). International Journal of Neonatal Screening, 2023, 9, PMID: 37873846, FI: 3.5

Martinez DAS*, Quilez-Cutillas A, Jimenez-Labaig P et al. Current professional standing of young medical oncologists in Spain: a nationwide survey by the Spanish Society of Medical Oncology + MIR section. Clinical & Translational Oncology, 2023, 25, 796-802, PMID: 36418642, FI: 3.4

Ramos Elbal E, Fuster JL, Campillo JA, ..., Minguela A*. Measurable residual disease study through three different methods can anticipate relapse and guide pre-emptive therapy in childhood acute myeloid leukemia. Clinical & Translational Oncology, 2023, 10.1007/s12094-022-03042-z [doi], PMID: 36598635, FI: 3.4

Gonzalez-Cao M, Puertolas T, Martinez-Vila C, ..., Cerezuela-Fuentes P et al. SARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry. Clinical & Translational Oncology, 2023, 25, 768-775, PMID: 36566266, FI: 3.4

Ramos Elbal E*, Fuster JL, Campillo JA, ..., Minguela A*. Measurable residual disease study through three different methods can anticipate relapse and guide early interventions in childhood acute lymphoblastic leukemia. Clinical & Translational Oncology, 2023, 10.1007/s12094-023-03251-0 [doi], PMID: 37368200, FI: 3.4

Boix F, Jimenez-Coll V, Legaz I, ..., Muro M. Higher Expression of Activated CD8(+) T Lymphocytes (CD8(+)CD25(+), CD8(+)CD69(+) and CD8(+)CD95(+)) Mediate Early Post-Transplant Acute Tubular Injury in Kidney Recipients. Frontiers in Bioscience-Landmark, 2023, 28, 119, PMID: 37395036, FI: 3.1

Pinero-Madrona A, Cerezuela-Fuentes P, Ruiz-Merino G et al. Lower limb cutaneous melanoma surgery: location matters. Archives of Dermatological Research, 2023, 10.1007/s00403-023-02571-z [doi], PMID: 36862181, FI: 3.0

Elen S, Bjorkman P, Zazzi M, ..., Bernal E et al. Low-level HIV viraemia during antiretroviral therapy: Longitudinal patterns and predictors of viral suppression. Hiv Medicine, 2023, 10.1111/hiv.13541 [doi], PMID: 37721192, FI: 3.0

Tyrkalska SD, Pedoto A, Martinez-Lopez A, ..., Candel S*, Mulero V*. Silica crystals activate toll-like receptors and inflammasomes to promote local and systemic immune responses in zebrafish. Developmental and Comparative Immunology, 2023, 138, 104523, PMID: 36055417, FI: 2.9

Martinez-Lopez A, Tyrkalska SD, Alcaraz-Perez F, ..., Mulero V. Evolution of LPS recognition and signaling: The bony fish perspective. Developmental and Comparative Immunology, 2023, 145, 104710, PMID: 37080369, FI: 2.9

Tyrkalska SD, Martinez-Lopez A*, Pedoto A, ..., Cayuela ML*, Mulero V*. The Spike protein of SARS-CoV-2 signals via Tlr2 in zebrafish. Developmental and Comparative Immunology, 2023, 140, 104626, PMID: 36587712, FI: 2.9

de Alba G, Camara-Ruiz M, Esteban MA, ..., Lopez-Olmeda JF*. Combined effects of rearing temperature regime (thermocycle vs. constant temperature) during early development and thermal treatment on Nile tilapia (Oreochromis niloticus) sex differentiation. Journal of Thermal Biology, 2023, 115, 103596, PMID: 37327616, FI: 2.7

Blanco G, Lopez-Aventin D, Pujol RM, ..., Muro M et al. High-throughput RNA sequencing of the T cell receptor alpha and beta chains for simultaneous clonality and biological analyses in Sezary syndrome. Journal of Clinical Laboratory Analysis, 2023, , e24982, PMID: 38115685, FI: 2.7

Velasco P, Bautista F, Rubio A, ..., Minguela A et al. The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP). Frontiers in Pediatrics, 2023, 11, 1269560, PMID: 37800011, FI: 2.6

Lopez-Garcia S, Sanz JL, Onate-Sanchez RE, ..., Garcia-Bernal D et al. In vitro biocompatibility of ammonia-free silver fluoride products on human dental pulp stem cells. Tissue & Cell, 2023, 86, 102283, PMID: 38113650, FI: 2.6

Moreno C, Ramos-Elbal E, Velasco P, ..., Fuster JL. Haploidentical vs. HLA-matched donor hematopoietic stem-cell transplantation for pediatric patients with acute lymphoblastic leukemia in second remission: A collaborative retrospective study of the Spanish Group for Bone Marrow Transplantation in Children (GETMON/GETH) and the Spanish Childhood Relapsed ALL Board (ReALLNet). Frontiers in Pediatrics, 2023, 11, 1140637, PMID: 37020654, FI: 2.6

Munoz-Megias ML, Sanchez-Fresneda R*, Solano F et al. The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria. Current Genetics, 2023, 69, 165-173, PMID: 37119267, FI: 2.5

Messina CM, Manuguerra S, Arena R et al. Contaminant-induced oxidative stress underlies biochemical, molecular and fatty acid profile changes, in gilthead seabream (Sparus aurata L.). Research in Veterinary Science, 2023, 159, 244-251, PMID: 37178628, FI: 2.4

Manzano JL, Martin-Liberal J, Fernandez-Morales LA, ..., Cerezuela-Fuentes P. Adjuvant dabrafenib and trametinib for patients with resected BRAF-mutated melanoma: DESCRIBE-AD real-world retrospective observational study. Melanoma Research, 2023, 10.1097/CMR.0000000000000888 [doi], PMID: 36988401, FI: 2.2

Muro-Perez M, Gonzalez-Martinez G, Martinez-Garcia P, ..., Muro M. Analysis of null deletion polymorphism of glutathione S-transferase theta (GSTT-1), associated with anti-GSTT-1 antibodies development in transplantation. International Journal of Immunogenetics, 2023, 50, 264-271, PMID: 37612787, FI: 2.2

Perez Vidal JR, Marin Sanchez MP*, Moreno Alarcon C, ..., Nieto Diaz A. A Combined Approach: Laparoscopic Partial Bladder Prior Transurethral Resection for Bladder Endometriosis-Case Report and Surgical Video Presentation. Urology, 2023, 178, 187-189, PMID: 37230270, FI: 2.1

Vazquez C, Garcia-Vazquez E, Carrilero B, ..., Segovia M. Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole. Revista da Sociedade Brasileira de Medicina Tropical, 2023, 56, PMID: 36700605, FI: 2.0

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Alfaro R, Llorente S, Gonzalez-Martinez G, ..., Muro M*. Clinical Significance of the Pre-Transplant CXCR3 and CCR6 Expression on T Cells In Kidney Graft Recipients. Transplantation Proceedings, 2023, S0041-1345(22)00883-1 [pii], PMID: 36621349, FI: 0.9

AYUDAS CONCEDIDAS EN 2023

TOTAL DE AYUDAS CONCEDIDAS

Nº Ayudas

3.01M €

Financiación

TOTAL DE AYUDAS RECURSOS HUMANOS CONCEDIDAS

Nº Ayudas

0.38M €

Financiación

TOTAL DE AYUDAS PROYECTOS I+D+i CONCEDIDAS

Nº Ayudas Europeas

1.22M €

Financiación Europea

Nº Ayudas Nacionales

0.53M €

Financiación Nacional

Nº Ayudas Regionales

0.12M €

Financiación Regional

TOTAL DE REDES CONCEDIDAS

Nº Ayudas

0.78M €

Financiación

OTRAS AYUDAS COMPETITIVAS CONCEDIDAS (MOVILIDAD, ORGANIZACIÓN DE EVENTOS CIENTÍFICOS, ...)

Nº Ayudas

0.0K €

Financiación

PROYECTOS DE I+D+i Y AYUDAS DE RRHH ACTIVAS EN 2023

TOTAL AYUDAS

RECURSOS HUMANOS

REDES

PROYECTOS INTERNACIONALES

PROYECTOS NACIONALES

PROYECTOS REGIONALES

INICIADA EN 2023

Nº Estudios

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

ACTIVOS EN 2023

255

Nº Estudios

161

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

FACTURACIÓN EN 2023

1.25M €

Facturado

Nº Tesis (6 con mención internacional)